with作介词的意思有用……、随着、支持、和……在一起等。
1.与……（在）一起，带着
Come with me. 跟我一起来吧。
I went on holiday with my friend. 我跟我朋友一起去度假。
Do you want to walk home with me? 你愿意和我一道走回家吗
2.（表带有或拥有）有……的，持有，随身带着
China is a very large country with a long history. 中国是一个具有历史悠久的大国。
3.（表方式、手段或工具）以，用
He caught the ball with his left hand. 他用左手接球。
She wrote the letter with a pencil. 她用铅笔写那封信。
4.（表材料或内容）以，用
Fill the glass with wine. 把杯子装满酒。
The road is paved with stones. 这条路用石头铺砌。
5.（表状态）在……的情况下，……地
He can read French with ease. 他能轻易地读法文。
I finished my homework though with difficulty. 虽然有困难，我还是做完了功课。
6.（表让步）尽管，虽然
With all his money, he is unhappy. 尽管他有钱，他并不快乐。
With all his efforts, he lost the match. 虽然尽了全力，他还是输了那场比赛。
7.（表条件）若是，如果
With your permission, I’ll go. 如果你同意我就去。
“with”的复合结构“with+宾语+宾语补足语”：
它在句中主要用作状语，表示伴随、原因、时间、条件、方式等；其中的宾语补足语可以是名词、形容词、副词、现在分词、过去分词、不定式、介词短语等。如：
(1) with+宾语+形容词
He often sleeps with the windows open. 他常开着窗睡觉。
Don’t speak with your mouth full. 不要满嘴巴食物说话。
(2) with+宾语+ 副词
He stood before his teacher with his head down. 他低着头站在老师面前。
He was lying on the bed with all his clothes on. 他和衣躺在床上。
(3) with +宾语+ 介词短语
She said good-bye with tears in her eyes. 她含着眼泪说了声再见。
The man was asleep with his head on his arms. 这个人头枕着胳膊睡着了。
(4) with+宾语+现在分词
He fell asleep with the lamp burning. 他没熄灯就睡着了。
I won’t be able to go on holiday with my mother being ill. 因为妈妈有病, 我无法去度假。